BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.2.1//EN TZID:America/Toronto X-WR-TIMEZONE:America/Toronto BEGIN:VEVENT UID:163@womenshealthresearchcluster.com DTSTART;TZID=America/Vancouver:20240923T090000 DTEND;TZID=America/Vancouver:20240923T100000 DTSTAMP:20250106T203051Z URL:https://womenshealthresearchcluster.com/events/modeling-neurovascular- cognitive-complications-after-preeclampsia-conditions-rodents/ SUMMARY:Modeling neurovascular-cognitive complications after preeclampsia-l ike conditions in rodents DESCRIPTION:\n\nSpeaker: Dr. Paula Warrington\, Associate Professor\ , School of Medicine\, Department of Neurology\, The University of Mississ ippi Medical Center Jackson\n\nDr. Junie Paula Warrington is an associate professor in the department of Neurology and associate director of the PhD Program in Neuroscience at the University of Mississippi Medical Center. She received a PhD in neuroscience from the University of Oklahoma Health Sciences Center in 2011 and has co-authored over 40 peer-reviewed manuscri pts and editorials and 1 book chapter. Dr. Warrington’s research has bee n continuously funded by a Pre- and Post-doctoral fellowship from the Amer ican Heart Association and a K99/R00 Pathway to Independence grant from th e National Institutes of Health. She received an administrative supplement award to link pregnancy-induced neurovascular impairment to Alzheimer's d isease. Her lab was recently supported by an NIH R56 award investigating m echanisms of seizures in pregnancy.\n\nDr. Warrington serves as co-Editor- in-Chief of the Journal of Neuroscience Research and consulting editor of AJP: Heart\, and served as digital media editor of Stroke. She has also gu est edited 3 special issues in scientific journals. Dr. Warrington serves on multiple committees at professional organizations such as the Society f or Neuroscience and Council on Hypertension. She has received numerous awa rds for her work\, including being featured on the cover of the Physiologi st magazine. The best part of her job is mentoring. She has mentored numer ous undergraduate\, high school\, medical\, and graduate students during h er career. Using preclinical animal models\, Dr. Warrington works on ident ifying pathophysiological mechanisms contributing to neurovascular abnorma lities and seizures in hypertensive disorders of pregnancy during antepart um\, peripartum\, and postpartum periods. Her work utilizes knockout and r eporter mouse models\, pharmacological\, molecular\, and behavioral approa ches to elucidate underlying mechanisms\, with the hope of identifying the rapeutic targets for prevention and treatment of pregnancy-associated neur ological sequelae. Her ultimate goal is to change the landscape of academi a by making it a more welcoming and supportive environment for future scie ntists.\n\nTalk summary:\n\nEpidemiological studies have shown an increase d risk of vascular dementia and mortality from Alzheimer’s disease in wo men with a history of preeclampsia. The underlying mechanisms are not full y known and preclinical models are not fully characterized. Using the redu ced utero-placental perfusion model in rats and mice\, Dr. Warrington's gr oup has shown evidence of neuroinflammation\, modest learning deficits\, r educed cerebral perfusion\, and increased expression of Alzheimer’s dise ase markers at 2 months postpartum.\n\nAgenda:\n\n9-9:45 am PDT: Speaker p resentation\n\n9:45-10:00 am PDT: Question and answer period ATTACH;FMTTYPE=image/jpeg:https://womenshealthresearchcluster.com/wp-conte nt/uploads/2024/11/Sep%20Banner.jpg CATEGORIES:Women’s Health Seminar Series END:VEVENT BEGIN:VTIMEZONE TZID:America/Vancouver X-LIC-LOCATION:America/Vancouver BEGIN:DAYLIGHT DTSTART:20240310T030000 TZOFFSETFROM:-0800 TZOFFSETTO:-0700 TZNAME:PDT END:DAYLIGHT END:VTIMEZONE END:VCALENDAR