BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.2.1//EN TZID:America/Toronto X-WR-TIMEZONE:America/Toronto BEGIN:VEVENT UID:177@womenshealthresearchcluster.com DTSTART;TZID=America/Toronto:20250915T120000 DTEND;TZID=America/Toronto:20250915T130000 DTSTAMP:20250916T130705Z URL:https://womenshealthresearchcluster.com/events/sex-anxiolytics-and-psy chosocial-stress-vulnerabilities-to-aging-and-alzheimers-disease/ SUMMARY:Sex\, Anxiolytics\, and Psychosocial Stress: Vulnerabilities to Agi ng and Alzheimer’s disease DESCRIPTION:https://youtu.be/o7KzfKxmZZs\n\nSpeaker: Dr. Holly Hunsberger\, Assistant Professor\, Foundational Sciences and Humanities\, Chicago Medi cal School\n\nDr. Hunsberger obtained her PhD in behavioral neuroscience f rom West Virginia University under the mentorship of Dr. Miranda Reed\, wh ere she studied glutamate’s role in Alzheimer’s disease (AD). From the re\, she secured a postdoctoral T32 fellowship at Columbia University with Dr. Christine Denny\, where she discovered her passion for understanding women’s health throughout aging and AD. Her initial postdoc work examini ng sex differences in anxiety and cognitive decline in AD mice earned her a K99/R00 career transition award through the NIA. This translational work was recently published in Biological Psychiatry. Holly began a faculty po sition at Rosalind Franklin University in November 2021. In her independen t laboratory\, Holly continues to examine sex differences in AD\, as well as the AD exposome\, which encompasses the unique experiences of each indi vidual\, including their genetics\, lifestyle\, injuries\, education\, med ications\, social networks\, and socioeconomic status. Each of these plays a role in disease progression and development\, but it is unclear how and when this occurs. Her lab studies various external perturbations using no vel behavioral and in vivo imaging techniques\, as well as brain-wide micr oscopy.\n\n \;\n\nTalk summary: This talk will focus on the AD exposom e and how different environmental factors can contribute to AD risk throug h a sex difference lens. Dr. Hunsberger will begin discussing the sex-spec ific impact of anxiety on cognitive decline\, and then will focus on drugs that are used to treat affective disorders and how those drugs could be h armful in AD patients. From there\, she will consider novel therapeutics t hat could be used to treat both mood and cognitive decline. Next\, she wil l examine how stress exacerbates anxiety and AD phenotypes and how AD male and female mice respond to different stressors. Lastly\, she will talk ab out menopause as a risk period for developing cognitive decline\, mood dis orders\, and dementia as a future direction.\n\n \;\n\nAgenda:\n\n12:0 0-12:45 pm EDT: Speaker presentation\n\n12:45-1:00 pm EDT: Question and an swer period\n\nRegister here ATTACH;FMTTYPE=image/jpeg:https://womenshealthresearchcluster.com/wp-conte nt/uploads/2025/07/1.png CATEGORIES:Women’s Health Seminar Series END:VEVENT BEGIN:VTIMEZONE TZID:America/Toronto X-LIC-LOCATION:America/Toronto BEGIN:DAYLIGHT DTSTART:20250309T030000 TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT END:DAYLIGHT END:VTIMEZONE END:VCALENDAR