BEGIN:VCALENDAR VERSION:2.0 PRODID:-//wp-events-plugin.com//7.2.2.1//EN TZID:America/Toronto X-WR-TIMEZONE:America/Toronto BEGIN:VEVENT UID:183@womenshealthresearchcluster.com DTSTART;TZID=America/Toronto:20260413T120000 DTEND;TZID=America/Toronto:20260413T130000 DTSTAMP:20250821T123225Z URL:https://womenshealthresearchcluster.com/events/translational-impacts-o f-pet-neuroimaging-and-womens-mental-health-postpartum-depression-and-anor exia-nervosa/ SUMMARY:Translational Impacts of PET Neuroimaging and Women's Mental Health : Postpartum Depression and Anorexia Nervosa DESCRIPTION:Speaker: Dr. Jeffrey Meyer\, Professor\, Department of Psychiat ry\, University of Toronto\nTier 1 Canada Research Chair in the Neurochemi stry of Major Depression\nHead of the Neurochemical Imaging Program in Moo d Disorders in the Brain Health Imaging Centre at CAMH\n\nDr. Meyer specia lizes in applying positron emission tomography to identify markers of biol ogical change in the midst of major depressive episodes and common comorbi d illnesses\; and then translate these into novel approaches for preventio n and overcoming treatment resistance. He has more than 150 peer-reviewed papers\, and led over 20 papers published in JAMA Psychiatry\, Lancet Psyc hiatry\, American Journal of Psychiatry\, Brain and Proceedings of the Nat ional Academy of Sciences. These findings include discovery of a new dieta ry supplement to prevent depressed mood in early postpartum\, discovering the first strong evidence for inflammation in the brain during major depre ssive episodes\, OCD\, long COVID\, and traumatic brain injury with chroni c symptoms\; that monoamine oxidase A and B level is elevated in affect mo dulating brain regions during major depressive episodes and several specif ic high risk states for major depressive episodes. He also established the 80% therapeutic occupancy rule for selective serotonin reuptake inhibitor s. Dr. Meyer has received the AE Bennett Award from the Society of Biologi cal Psychiatry\, the Distinguished Investigator Award from Brain and Behav ior Research Foundation\, the Innovations award from the Canadian College of Neuropsychopharmacology\, the Samarthji Lal Award from the Graham Boeck h Foundation\, the John Dewan Prize from the Ontario Mental Health Foundat ion and the Royal College Medal Award in Medicine for outstanding contribu tions to psychiatric research.\n\n \;\n\nTalk summary: Brain imaging c an be applied to identify biological changes associated with risk for\, or state of\, psychiatric illness. Such findings may suggest novel approache s for prevention and treatment. This talk will summarize two directions of research at different phases of development in the transition between dis covery of biological changes in brain and therapeutic impact. The first se t of studies\, will review how changes in level of the monoamine oxidase A (MAO-A) enzyme are associated with risk for major depressive episodes and the role of MAO-A in postpartum depression\; and how a dietary supplement designed to compensate for elevated MAO-A level shows protection against depressive symptoms in postpartum. Prevention of postpartum depression is important given its 13% prevalence and historical lack of widespread preve ntative approaches. The second set of studies will focus on new data inves tigating the relationship between a brain marker of inflammation and anore xia nervosa (AN). The data shown is among the largest magnitude biological changes reported in AN. Such information may be crucial to advance new ph armacological treatment\, an issue of key importance given the lack of evi dence based pharmacological treatment in AN.\n\n \;\n\nAgenda:\n\n12-1 2:45 pm EDT: Speaker presentation\n\n12:45-1:00 pm EDT: Question and answe r period\n\nRegister here ATTACH;FMTTYPE=image/jpeg:https://womenshealthresearchcluster.com/wp-conte nt/uploads/2025/07/8.png CATEGORIES:Women’s Health Seminar Series END:VEVENT BEGIN:VTIMEZONE TZID:America/Toronto X-LIC-LOCATION:America/Toronto BEGIN:DAYLIGHT DTSTART:20260308T030000 TZOFFSETFROM:-0500 TZOFFSETTO:-0400 TZNAME:EDT END:DAYLIGHT END:VTIMEZONE END:VCALENDAR